Goofs for
Fantastic Voyage (1966) More at IMDbPro »

• Crew or equipment visible: Shadow visible on the right hand wall as the camera pulls back to see the large control room for the first time[widescreen only].
  
  
• Continuity: The heart rate shown on the monitors, the heart rate heard by the Proteus crew, and the heart rate specified by the technicians aren't even close to matching.
  
  
• Crew or equipment visible: Wires visible throughout the "swimming" sequences.
  
  

• Errors made by characters (possibly deliberate errors by the filmmakers): When the nurse is fitting the needle to the hypodermic, she is not wearing surgical gloves, although the machine operators are.
  
  
• Factual errors: The patient's red blood cells, shown in the various scenes of the miniaturized submarine traveling through blood vessels, are nucleated, which is incorrect. Mammalian, and therefore human, red blood cells have no nuclei; nucleated red blood cells are found in most other animals, however, such as birds, reptiles, amphibians, fish, etc.
  
  
• Revealing mistakes: The crewmen reported before the sterilization procedure that Benes' heart rate was 32 beats per minute and it was his respiration that was 6 breaths a minute. But even so, these heart rates were still inconsistent.
  
  
• Revealing mistakes: A slice of Capt. Bill Owens' right side of head is missing in the scene in the vein after the arterial-venous fistula incident, probably due to a mismatched matte. (Approx 44 minutes, 57 seconds into the film)
  
  
• Revealing mistakes: As the car disappears down the lift, delivering Grant to CMDF, it should vanish as it is hidden by the hole. Instead the special effects crew elected to shrink the image; we see at least 20 feet of elevation change at the back wall but the car is still visible at foreground.
  
  
• Crew or equipment visible: When Grant is being driven up the ramp at CMDF, a shadow of crew member holding a boom is visible at first turn and another shadow is visible at the top of the ramp just before the camera pulls back.
  
  
• Continuity: The number on the nose of the Boeing 707 changes from 6746 to 7744.
  
  
• Factual errors: The amount of radioactive material for the sub would not need a lead carrying case. Grant proves this by removing the container from the case with no protection and handing it to Owens who inserts it into the reactor, again bare-handed.
  
  
• Factual errors: The scuba equipment has a low-pressure hose running between the tank and the face-mask. The face-mask appears to have a regulator built in (the silver disk). The regulator reduces the pressure from the tank to a pressure the diver can breathe. The typical pressure of an open SCUBA system with a regulator tank is 200-300 atmospheres. This would blow out the hose as soon as the air was turned on.
  
  
• Continuity: When Grant's car starts to descend on the elevator, it is parked on concrete. When he leaves the car at CMDF, it appears the material has been changed to dirt.
  
  
• Crew or equipment visible: Wires are visible when the sub is in the lymphatic system just prior to moving to the inner ear. Wires show on the sub, the reticulated fibers, and even on the "invading bodies."
  
  
• Errors made by characters (possibly deliberate errors by the filmmakers): Grant is introduced as the man who retrieved Benes and a frogman in "the war." However, Grant, played by Stephen Boyd was only 8 years old at the beginning of WWII. He would have been closer the the correct age for Korea, however, the Korean Conflict is generally referred to as "Korea" just as a later conflict was just called "Vietnam."
  
  
• Plot holes: At the end, when the "micronauts" escape Benes' body through the tear ducts, there are just the four of them that make it out. As they left the sub and the fifth member of their crew still in the body (their mass admittedly "digested" by a white blood cell but still all within Benes' body) then the body (and perhaps the entire operating room) would be destroyed by that mass returning to its full size - thus killing Benes, whom they were intending to save. (Asimov's novelization corrects this.)
  
  

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