- Jodie Foster was initially offered the role of Alice.
- Jerry's cab license is issued in the name of "Raffi Paloulian," a script clearance researcher on the film and friend of screenwriter Brian Helgeland. Paloulian also appears as an extra.
- Jerry runs into a theatre showing Ladyhawke (1985), also directed by Richard Donner.
- Director Richard Donner is an animal-rights and pro-choice activist. The newsstand where Jerry picks up his newspapers has an anti-fur slogan on it. See also Lethal Weapon 3 (1992).
- Jerry's cab is numbered 1S48. The bus that Jerry hooks up to the fruit cart is 1648. This is a tribute to stuntman Harry Wowchuk who worked on this movie and who was born on October 16, 1948 and who has worked with Richard Donner and Joel Silver on three movies.
- The doctor who lets Julia Roberts into the restricted area to see Mel Gibson handcuffed to the bed is Gibson's younger brother Donal Gibson.
- All of the scenes at the horse farm were shot at Lionshare Farm in Greenwich, CT, which is owned by United States Equestrian Team member Peter Leone. Leone coached Julia Roberts through the scene at the end where she rides her horse across a field at a gallop.
- The character names "Dr. Jonas" (Patrick Stewart), and "Agent Lowry" (Cylk Cozart), were both named after British character actor Morton Lowry, who portrayed the school teacher Mr. Jonas in How Green Was My Valley (1941).
- In the original script, the theme song was to be "Blue Moon".
- When Alice Sutton returns to Jerry Fletcher's torched apartment, looking for clues on his conspiracy wall, the mugshot of Ezekiel Walters is played by a shot of Brian Helgeland, the writer.
- When Jerry is in the hospital for the first time (where he writes the word Geronimo on the wall), the room number on the hospital door is briefly visible: 322. This number is well-known in conspiracy circles as being the address of the Skull & Bones society at Yale University, which is said to have the skull of Geronimo in its possession.
- In the movie several times an earthquake is referenced that took place in southern coast with a magnitude of 7.3 during a presidential visit. There indeed happened a 7.3 earthquake in North-West part of Turkey in 1999, just to be followed by a presidential visit.
- Director Cameo: [Richard Donner] Jerry's cab passenger in the opening credits.
- According to director Richard Donner, Mel Gibson improvised the opening scenes in which his character expounds his conspiracy theories to a succession of passengers.
>>> WARNING: Here Be Spoilers <<<
Trivia items below here contain information that may give away important plot points. You may not want to read any further if you've not already seen this title.
- SPOILER: Jerry Fletcher's grave marker lists his date of death as 10-9-1997 or October 9th. John Lennon, who is referenced in dialogue and image several times in the film, was born on October 9th.
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