- The movie was first optioned in 1982 by producers Ivan Reitman, Joe Medjuck and Michael C. Gross. Douglas Adams wrote three drafts for them per his contract. During this time, Medjuck and Gross were considering Bill Murray or Dan Aykroyd to play Ford Prefect, but then Aykroyd sent them his idea for Ghost Busters (1984) and they did that movie instead.
- Douglas Adams's head appears as a planet during Slartibartfast's tour of the galaxy.
- This film was in "Development Hell" for over twenty years. At one point, Douglas Adams insisted it would be made "sometime before the last Trump". Just prior to his death, a deal was almost in place with Jay Roach directing and starring Hugh Laurie (Arthur), Jim Carrey (Zaphod Beeblebrox) and the late Nigel Hawthorne (Slartibartfast).
- John Malkovich's character, a religious leader, was created especially for the movie by Douglas Adams.
- This is the ninth version of the "Hitchhiker's Guide". It has previously appeared as a radio series, two record albums, novels, a television series ("The Hitch Hikers Guide to the Galaxy" (1981)), a computer game, a stage show, a comic book, a video game (The Hitchhiker's Guide to the Galaxy (1984) (VG)) and a towel.
- The music played the first time the book is introduced is called "The Journey of the Sorcerer". The original version by Eagles served as the theme song for the original BBC Radio series, then later for the BBC Television series, "The Hitch Hikers Guide to the Galaxy" (1981).
- In a reference to the 1980s TV series, "The Hitch Hikers Guide to the Galaxy" (1981), when Zaphod first appears, he is eating from a packet of Starbix cereal (the "nasty but nourishing" Starbix packet can be seen in episode 5 of the TV show). Later, during the missile chase scene, Zaphod deliberately saves the cereal box as people and objects are sliding around the bridge.
- The note that Ford uses in the pub to buy six pints "and keep the change" is a £50 Bank of England note with the engraving of Sir John Houblon on the back. In the original 1978 radio version and in "The Hitch Hikers Guide to the Galaxy" (1981), it was "a fiver".
- After Jay Roach decided to pass on directing the movie, he brought the property to Spike Jonze. Jonze also passed, but suggested Nick Goldsmith and Garth Jennings (also known as Hammer and Tongs, also soon-to-be former music video directors), who accepted.
- Jack Davenport was considered for the role of Arthur Dent, but in the end it was decided he was simply too good-looking for the role of the ultimate everyman Dent. Douglas Adams had originally wanted Hugh Grant to also play Arthur, but the idea was nixed.
- A painting of Douglas Adams and his wife Jane Belson appears on the Heart of Gold. Other Adams cameos include a few handles on some cupboards in Humma Kavula's office being shaped like Adams' nose.
- The car that Ford Prefect "introduces himself to" is actually a Ford Prefect, from whence Ford got his "Earth name". Despite being a Ford, the car was never manufactured or sold in the United States, but produced in Ireland, the UK, Malaysia and New Zealand, and sold in Europe, Asia and Australia between 1938 and 1959.
- Belgium (which, according to the original radio series, is the most unspeakably rude word there is) can be heard in the movie three or so times.
- The Vogon written language seen on their release forms as well as in a bilingual caption in the Magrathean video which says "Information Deleted", is actually a form of English. Pitman shorthand, once taught to hundreds of thousands of office-workers mainly in the British Commonwealth, is a series of straight and curved strokes meant to write down sounds much faster than regular writing. As discussed in a book about the movie, the Vogons use a slightly blocky but recognizable form of "Pitman 2000", the most recent version of Pitman shorthand published in 1970. It occurs in the Vogon release forms, posters on the wall which say "Fire Exit Escape Map" (over a hopelessly confusing maze of arrows with a spot at the center saying "You Are Here") and "Are you depressed? Destruction Therapy!"
- Shada, the prison planetoid of the Time Lords, can be seen in the background during the factory floor scene on Magrathea. Shada was featured in an un-aired serial of "Doctor Who" (1963) that Douglas Adams wrote.
- In one shot, the Apple Mac logo is visible on the side of Deep Thought, the giant computer. Douglas Adams owned the first two Apple Macintosh computers delivered to the United Kingdom, while Stephen Fry (the voice of the Book) owned the third. Both men were/are keen advocates of the Mac.
- The Magrathean holomessage appears as if it would become three dimensional with red/green 3-D glasses, but it is only a gimmick. It doesn't actually become 3D, and if you look closely, he's only rimmed with red and blue. If it were a real 3D effect his whole face would be blurred with red/blue overlays.
- The initial scene, with the dolphins prancing about, is a dolphin show in the "Loro Parque" Zoo, in Puerto de la Cruz, Tenerife, Spain - which is also the only place in Europe to feature an "Orca Ocean", as well as having the largest parrot collection in the world.
- The phone which Arthur uses in the first part of the film is a Nokia 7610.
- The hymn sung by the Jatravartidian followers of Humma Kavula was recorded at St. Martin's Church, Highgate, London on 19 June 2004. The hymn was sung by several hundred untrained members of the public invited to the recording via a call for singers circulated on the internet.
- In a chaotic scene shot in London, fans can spot Douglas Adams's brother James Thrift, sister Jane Garnier and daughter 'Polly Jane Adams' rushing about in the general panic, as the earth is destroyed by the Vogons.
- Bill Murray was also considered for the part of Zaphod Beeblebrox, along with Will Ferrell. But after Sam Rockwell's audition, director Garth Jennings immediately chose him.
- Robert Downey Jr. and Johnny Depp were both considered to play Zaphod Beeblebrox.
- The pub which Ford takes Arthur to in the beginning of the film is called the Beehive Pub. It is in Hertfordshire, England.
- When Ford and Zaphod first greet each other on the Heart of Gold, Zaphod calls Ford "Ix" and then quickly corrects himself. In the novel, "Ix" was a nickname that Ford's childhood schoolmates gave him, which, according to the book, translates as "boy who is not able satisfactorily to explain what a Hrung is, nor why it should choose to collapse on Betelgeuse Seven."
- The old lady sitting at the street side table oblivious to or uninterested in what's going on around her is Douglas Adams's mother. The director didn't give any acting directions to her or anybody else in the scene for what they were suppose to do, to simulate chaos, so she just sat there reading a newspaper.
- The fancy dress party contains several references to Douglas Adams' 40th birthday party. At the real party, Adams introduced Darwinian Evolutionist Richard Dawkins to the future Mrs Dawkins, actress Lalla Ward. In the film, Arthur is seen reading Dawkins' book, "The Selfish Gene", when he meets Tricia, who is dressed as Charles Darwin. Adams and Dawkins became very good friends after Adams received a fan letter from him.
- The producers have stated that this film is not a literal translation of the books (just as the books were not a literal translation of the original radio show), but all of the new ideas and characters came from Douglas Adams himself. The hired writer simply came aboard to improve structure and make the screenplay more coherent.
- The disembodied head delivering the Magrathean warning message was performed by Simon Jones, who played Arthur in the original radio/TV series.
- Simon Jones, who played Arthur in all previous audio/video versions (and was, in fact, originally hand-picked by friend Douglas Adams for the role), makes a brief appearance as the Magrathean "greeting/threat" holomessage. This marks another slight deviation from the other Guide incarnations, as all other versions used the actor who played Slartibartfast for the holomessage.
- Some additional shots were filmed to fit in with Arthur waking up at the beginning of the movie. In one shot (included in an early trailer, but cut from the film, and not on the DVD), Arthur's identification as a BBC employee can be seen. The original Hitch Hiker's radio and TV versions were produced by the BBC.
- Easter Egg: The DVD includes an "Improbability Drive" item on every menu. Clicking this takes you to a random point in one of the bonus features. If you use it several times, you get to see a strange cartoon, which is apparently the same one Deep Thought watches in the movie.
- The relevance of Sector ZZ9 is the fact that in the UK if a person has NFA (No fixed Abode (No place to live)) then the POSTCODE is recorded as ZZ99 3VZ, thus Both Trillian and Arthur come from Sector ZZ9 and thanks to the Vogons they are both of NFA.
- Several minutes into the credits, a final Guide entry is shown. This is the "careless words/problem of scale" entry, well known to fans of other incarnations of the Guide.
- When Ford and Arthur drink at the pub early in the film, a middle-aged blonde can be seen watching them. According to the DVD commentary, this actress (Su Elliot) played Trillian in the London stage version of the story - a fact the director was unaware of until the day of shooting.
- The scene in which Arthur learns the Guide's sole entry for earth is "Harmless" and that the updated version was to be "Mostly Harmless" was filmed but didn't make the final cut (it is included as a bonus deleted scene on the DVD). It would have been seen when Arthur and Ford arrive on the Vogon ship.
- One major change originally made for the film (and apparently the only one not originating from Douglas Adams) was that Trillian was to have been revealed as being only half-human. This plot point is referenced in pre-release publicity including the film-tie-in reissue of the original novel, cast and director interviews and the official "making of" book. Before release, however, this plot point was deleted from the film.
- During the scene where the Vogons are preparing to destroy earth, a large radio dish can be seen (surrounded by a sheep paddock). It is the Jodrell Bank Radio Telescope in Cheshire, England.
- The sound made by the bread toasting knife held by Trillian when it heats up is the same as the sound made by lightsabres in Star Wars when they are energized. Because of this, Lucasfilm is given special thanks in the credits.
- The names of all five books - Hitchhiker's Guide to the Galaxy, Restaurant at the End of the Universe, Life the Universe and Everything, So Long and Thanks for All the Fish, and Mostly Harmless - are each mentioned throughout the course of the movie. The last, however, ended up on the cutting room floor and can be seen in the Deleted Scenes of the DVD.
- Oliver Postgate auditioned for the voice of the Book.
- Johnny Depp, who is a huge fan of Douglas Adams work, had expressed great interest in playing the role of Zaphod Beeblebrox.
- Mr. Prosser is depicted with dark eyes and a droopy mustache. In the book, it explains that he is actually a direct descendant of Ghengis Kahn, although he doesn't know it.
- When hurriedly giving possible questions to what the answer 42 might mean Arthur's suggestion of "How many roads must a man walk down?" is a reference to the Bob Dylan song "Blowin' In The Wind". It's the opening line to the song.
- Sam Rockwell has said in interviews that his portrayal of Zaphrod was influenced by three people: Bill Clinton, Elvis Presley and Vince Vaughn.
- Faint screams can be heard a moment before Mr. Prosser speaks. In the book, Mr. Prosser is a direct male-line descendant of Genghis Khan, the reason why he wears little fur hats and often hears a thousand hairy horsemen shouting in his head.
- As the emergency escape pod crashes on Vogsphere, the sound made by it is the same as the plane from the end of 'In the Flesh' the first track on Pink Floyd's The Wall. Douglas Adams was a personal friend of Pink Floyd and even played at one of their shows.
- The nightgown/bathrobe Arthur Dent wore was the most expensive and difficult of all costumes (including Zaphod's heads and Humma's eyes). The fabric had to be sewn on stage and was flown in from Turkey.
- Deep Thought reveals the answer to the ultimate question 42 minutes into the film.
- According to Douglas Adams' notes, he wanted the name of the character "Slartibartfast" to sound extremely rude, but still pass BBC's rules on what could be broadcast - he actually started with "Phartiphukborlz" and changed it, bit by bit, until it was acceptable.
>>> WARNING: Here Be Spoilers <<<
Trivia items below here contain information that may give away important plot points. You may not want to read any further if you've not already seen this title.
- SPOILER: While waiting in the queue at the Vogon Prisoner Detention Centre, Marvin (the one from the TV version "The Hitch Hikers Guide to the Galaxy" (1981)) can be seen waiting in line. As Arthur (from this film) passes him, he gives a double take.
- SPOILER: As the Heart of Gold Spaceship travels through "improbability" it quickly transforms into many strange shapes (including a rubber duck) in the very final transformation at the end of the film it quickly transforms into the face of author/creator Douglas Adams.
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