When Iris is browsing Amanda's movie collection, you can see very clearly on the shelf the film Enigma (2001), which Kate Winslet starred in.
The interior sets for Amanda's house were built on a sound stage and cost approximately $1 million, without exterior walls, a roof, plumbing, heating and electricity.
On an episode of "The Tonight Show with Jay Leno" (1992), Dustin Hoffman said that his cameo in the film was not scripted and unplanned. He was driving by the Blockbuster shown in the film and saw all of the cameras and equipment so he decided to stop in and see what was happening. Because he knew director Nancy Meyers, they worked up a scene which ultimately made the final cut.
When Iris and Miles are browsing in the video store there is a cameo by Dustin Hoffman just after Jack Black performs the theme from The Graduate (1967) and in the next shot the movie cover right between Iris and Miles is Marathon Man (1976) both starring Hoffman.
Jude Law has a real-life daughter named Iris. His character Graham's sister's name is Iris.
In the Special Features, Cameron Diaz claims this movie is her most physical due to all the running she had to do.
Amanda's stack of books on the plane to England are: "The Kite Runner" by Khaled Hosseini, "The Power of Now" by Eckhart Tolle, "Atonement" by Ian McEwan, "Team of Rivals: The Political Genius of Abraham Lincoln" by Doris Kearns Goodwin, "Harry Potter and the Sorcerer's Stone" by J.K. Rowling, "Bob Dylan Chronicles" by Bob Dylan, "The Corrections" by Jonathan Franzen, "Runaway" by Alice Munro, "The Wisdom of Forgiveness: Intimate Journeys and Conversations" by Dalai Lama and Chan Victor.
When Amanda first arrives at Rosehill Cottage in Surrey, she buys lots of food and drink and settles down to watch the TV. The program she is watching is "Little Britain" (2003). Jude Law, a huge fan of the program, insisted they use that show, he personally chose what sketch was shown.
Miles hums the score for Driving Miss Daisy (1989) at the DVD store and says, "Hans. Very unexpected." Hans Zimmer wrote this and that film's score.
While in Blockbuster, Jack Black's character picks up a copy of The Mission (1986) and comments on it being a great score. This movies' score composer Hans Zimmer, has said that that particular movie score is the one that inspired him.
Several references to Ennio Morricone: The movie's main theme starts with the same five chords as "Deborah's theme" from Once Upon a Time in America (1984), Miles urges Iris to rent The Mission (1986) because of its score, and the main theme of Nuovo cinema Paradiso (1988) plays on Miles' car stereo the first time he and Iris meet (he even tells her that it was composed by Ennio Morricone).
This movie is mentioned specifically in emails between South Carolina Governor Mark Sanford and his mistress as very close to their situation.