The airplane used in the flight sequences is actually a full-size 737 used for training purposes at the Vincennes University Aviation Technology Center in Indianapolis.
Director/Screenwriter Trademark: [Jefferson Moore] As was the case with his two previous films, 'La Sposa' (2004) and 'The Perfect Stranger' (2005), 'Another Perfect Stranger' is also set in the city of Chicago - Moore's "adopted hometown".
Novelist David Gregory, author of 'A Day with a Perfect Stranger', upon which the movie is based, appears on the airplane as the voice of the captain.
Blue-eyed blonde Ruby Marie Lewis had to be 'transformed' into a brown-eyed brunette to become a grown up version of Stella Davis from the first film. She was still sporting her new look when she participated in her sister's wedding, which took place shortly after filming wrapped.