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The following FAQ entries may contain spoilers. Only the biggest ones (if any) will be covered with spoiler tags. Spoiler tags are used sparingly in order to make the page more readable.
For detailed information about the amounts and types of (a) sex and nudity, (b) violence and gore, (c) profanity, (d) alcohol, drugs, and smoking, and (e) frightening and intense scenes in this movie, consult the IMDb Parents Guide for this movie. The Parents Guide for Quarantine can be found here.
No. Quarantine is a remake of Spanish film-maker Jaume Balagueró's [Rec] (2007). Balagueró wrote the original script for [REC], which was then adapted for Quarantine by American film-makers Drew and John Eric Dowdle (also director).
Not quite. The victims of the infection in Quarantine are still-living humans, much in the vein of the Infected from the 28 Days Later series. The sick are infected with a rare, deadly virus: in this case, a mutant strain of rabies that causes symptoms to manifest within a manner of minutes and causes the carrier to react in a homicidal manner. The sick can also be compared to those in I Am Legend (2007) in that they appear to be capable of rudimentary cognitive abilities that enable them to achieve various tasks outside of violence.
Near the end of the film, Angela and Scott find their way into the attic. In the attic they find dozens of cages filled with rats. Also in the attic are numerous medical files stored on a desk beneath a bulletin board. On the bulletin board are newspaper and magazine articles about a man who defected from a doomsday cult, claiming that they had perfected an "Armageddon virus," and an article about scientists attempting to discern why and how all life was wiped out on an island in the South Pacific. Given the lab rats, medical equipment, and patient files, coupled with the article about the cult defector, it would seem that the Man from Boston was the defector and was attempting to synthesize a cure for the virus. As such, he had infected rats, one of which escaped. The rat then bit Max the dog, and possibly Briana and Mrs. Espinoza, starting the outbreak.
When Scott goes up into the crawlspace to see if there was a way out, something attacks the camera briefly, then comes down from the crawlspace (not being noticed by Angela and Scott because of the surrounding darkness). Looking closely, it seemed to be a young child that was infected.
When Angela and Scott make it to the attic and find all the rats and newspaper clippings about rabies and armageddon, they stumble upon a tape recorder, turn it on, and what they hear is an unintelligible low-pitched sound. There are two possible reasons for this - one, since the power had been cut off to the building, one can ascertain that the tape recorder was running only on batteries, and the batteries had become so low that the recorder would not play to an intelligible speed. The second possibility is that the recorded was set at half-speed and neither the reporter nor the camera man knew how to adjust it. Either way, the tape sounds like it's an audio journal the cult member was keeping - if you speed the tape up about 70% you can hear the original tenant saying: "It appears the spread will be impossible to contain. November (7th?), something unexpected has happened. Our brothers in the east have come under suspicion..." The whole recorder may have been a slight joke on the director's part, taking a shot at horror movies that have conveniently placed recordings that show up out of nowhere and explain everything to the audience. REC has been accused of this, as the tape recorder in the original version detailed the origins of the virus rather than letting the audience figure any of it out by themselves.
Fletcher, the fireman who fell from Mrs. Espinoza's floor to the floor of the lobby stories below, seems to have been bitten before he fell. The viewer can presume that Mrs. Espinoza attacked him upstairs, causing him to stumble backwards and fall over the railing.
Children often have metabolisms of different speeds compared to adults. This could explain why Briana had been sick for at least a week before rapidly showing symptoms of the rabies. [REC], the original movie, also briefly mentions that different blood types cause the symptoms to appear at different speeds. This too could have something to do with it.
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