Gervais, who recently signed a deal to host his fourth Golden Globes ceremony in January, will voice the villainous Ika Chu, a cat who plans to rid the town of Kakamucho of its feline inhabitants.
Previously announced Michael Cera will voice Hank, a dog who dreams of becoming a heroic warrior and must save his community.
Other cast members on board include Samuel L Jackson, Mel Brooks, George Takei, Gabriel Iglesias, Aasif Mandvi, Djimon Hounsou, Michelle Yeoh, Sandra Tsing Loh, Mel B and Heavenly Joy Jerkins.
Rob Minkoff, Yair Landau and Susan Purcell produce. Chris Bailey and Mark Koetsier are directing from a screenplay by Ed Stone and Nate Hopper. Mel Brooks serves as executive producer alongside Reginald Hudlin and Pietro Ventani.
Open Road Films will release in the Us