Most Popular Plague Movies and TV Shows
- Movies or TV
- IMDb Rating
- Instant Watch Options
- In Theaters
- On TV
- Release Year
1. Gladiator (2000)
R | 155 min | Action, Adventure, Drama
A former Roman General sets out to exact vengeance against the corrupt emperor who murdered his family and sent him into slavery.
Votes: 1,239,346 | Gross: $187.71M
2. Beauty and the Beast (2017)
PG | 129 min | Family, Fantasy, Musical
A selfish prince is cursed to become a monster for the rest of his life, unless he learns to fall in love with a beautiful young woman he keeps prisoner.
Votes: 246,465 | Gross: $504.01M
3. 28 Days Later... (2002)
R | 113 min | Drama, Horror, Sci-Fi
Four weeks after a mysterious, incurable virus spreads throughout the UK, a handful of survivors try to find sanctuary.
Votes: 350,898 | Gross: $45.06M
4. V for Vendetta (2005)
R | 132 min | Action, Drama, Sci-Fi
In a future British tyranny, a shadowy freedom fighter, known only by the alias of "V", plots to overthrow it with the help of a young woman.
Votes: 966,899 | Gross: $70.51M
5. Contagion (2011)
PG-13 | 106 min | Action, Drama, Thriller
Healthcare professionals, government officials and everyday people find themselves in the midst of a worldwide epidemic as the CDC works to find a cure.
Votes: 203,688 | Gross: $75.66M
7. Medici (2016– )
TV-14 | 60 min | Biography, Drama, History
A political family drama set in Florence in the early fifteenth century. Cosimo de Medici finds himself at the helm of his banking dynasty when his father, Giovanni, dies suddenly.
8. The Stand (1994)
Not Rated | 361 min | Adventure, Drama, Fantasy
After a deadly plague kills most of the world's population, the remaining survivors split into two groups - one led by a benevolent elder and the other by a maleficent being - to face each other in a final battle between good and evil.
9. I Am Legend (2007)
PG-13 | 101 min | Drama, Sci-Fi, Thriller
Years after a plague kills most of humanity and transforms the rest into monsters, the sole survivor in New York City struggles valiantly to find a cure.
Votes: 644,142 | Gross: $256.39M
10. The Last of Us (2013 Video Game)
M | Action, Adventure, Drama
In a hostile, post-pandemic world, Joel and Ellie, brought together by desperate circumstances, must rely on each other to survive a brutal journey across what remains of the United States.
11. 12 Monkeys (1995)
R | 129 min | Mystery, Sci-Fi, Thriller
In a future world devastated by disease, a convict is sent back in time to gather information about the man-made virus that wiped out most of the human population on the planet.
Votes: 546,176 | Gross: $57.14M
12. Monty Python and the Holy Grail (1975)
PG | 91 min | Adventure, Comedy, Fantasy
King Arthur and his Knights of the Round Table embark on a surreal, low-budget search for the Holy Grail, encountering many, very silly obstacles.
Votes: 470,220 | Gross: $1.23M
13. The Mummy (1999)
PG-13 | 124 min | Action, Adventure, Fantasy
At an archaeological dig in the ancient city of Hamunaptra, an American serving in the French Foreign Legion accidentally awakens a mummy who begins to wreck havoc as he searches for the reincarnation of his long-lost love.
Votes: 371,456 | Gross: $155.25M
14. Maze Runner: The Death Cure (2018)
PG-13 | 143 min | Action, Sci-Fi, Thriller
Young hero Thomas embarks on a mission to find a cure for a deadly disease known as "The Flare".
Votes: 96,040 | Gross: $58.03M
16. Night of the Living Dead (1968)
Not Rated | 96 min | Horror
A ragtag group of Pennsylvanians barricade themselves in an old farmhouse to remain safe from a bloodthirsty, flesh-eating breed of monsters who are ravaging the East Coast of the United States.
Votes: 107,294 | Gross: $0.09M
17. The Return of the Living Dead (1985)
R | 91 min | Comedy, Horror, Sci-Fi
When two bumbling employees at a medical supply warehouse accidentally release a deadly gas into the air, the vapors cause the dead to rise again as zombies.
Votes: 50,340 | Gross: $14.24M
18. Inferno (I) (2016)
PG-13 | 121 min | Action, Adventure, Crime
When Robert Langdon wakes up in an Italian hospital with amnesia, he teams up with Dr. Sienna Brooks, and together they must race across Europe against the clock to foil a deadly global plot.
Votes: 142,671 | Gross: $34.34M
19. 12 Monkeys (2015–2018)
TV-14 | 42 min | Adventure, Drama, Mystery
Follows the journey of a time traveler from the post-apocalyptic future who appears in present day on a mission to locate and eradicate the source of a deadly plague that will nearly destroy the human race.
20. Pride and Prejudice and Zombies (2016)
PG-13 | 108 min | Action, Comedy, Fantasy
Five sisters in 19th century England must cope with the pressures to marry while protecting themselves from a growing population of zombies.
Votes: 47,352 | Gross: $10.91M
21. Dawn of the Dead (1978)
Unrated | 127 min | Horror, Thriller
Following an ever-growing epidemic of zombies that have risen from the dead, two Philadelphia S.W.A.T. team members, a traffic reporter, and his television executive girlfriend seek refuge in a secluded shopping mall.
Votes: 104,988 | Gross: $5.10M
22. The Brothers Grimm (2005)
PG-13 | 118 min | Action, Adventure, Comedy
Will and Jake Grimm are traveling con-artists who encounter a genuine fairy-tale curse which requires true courage instead of their usual bogus exorcisms.
Votes: 111,751 | Gross: $37.92M
23. The Seventh Seal (1957)
Not Rated | 96 min | Drama, Fantasy
A man seeks answers about life, death, and the existence of God as he plays chess against the Grim Reaper during the Black Plague.
24. Exodus: Gods and Kings (2014)
PG-13 | 150 min | Action, Drama, Fantasy
The defiant leader Moses rises up against Egyptian Pharaoh Ramses II, setting six hundred thousand slaves on a monumental journey of escape from Egypt and its terrifying cycle of deadly plagues.
Votes: 152,585 | Gross: $65.01M
25. The Last Witch Hunter (2015)
PG-13 | 106 min | Action, Adventure, Fantasy
The last witch hunter is all that stands between humanity and the combined forces of the most horrifying witches in history.
Votes: 88,018 | Gross: $27.37M
26. The Prince of Egypt (1998)
PG | 99 min | Animation, Adventure, Drama
An Egyptian prince learns of his identity as a Hebrew and his destiny to become the chosen deliverer of his people.
Votes: 110,100 | Gross: $101.22M
27. Warm Bodies (2013)
PG-13 | 98 min | Comedy, Horror, Romance
After a highly unusual zombie saves a still-living girl from an attack, the two form a relationship that sets in motion events that might transform the entire lifeless world.
Votes: 210,772 | Gross: $66.38M
28. Darkness Falls (2003)
PG-13 | 86 min | Fantasy, Horror, Mystery
A vengeful spirit has taken the form of the Tooth Fairy to exact vengeance on the town that lynched her 150 years earlier. Her only opposition is the only child, now grown up, who has survived her before.
Votes: 29,094 | Gross: $32.55M
29. The Ten Commandments (1956)
G | 220 min | Adventure, Drama
The Egyptian Prince, Moses, learns of his true heritage as a Hebrew and his divine mission as the deliverer of his people.
Votes: 58,400 | Gross: $93.74M
30. Dreamcatcher (2003)
R | 134 min | Drama, Horror, Sci-Fi
Friends on a camping trip discover that the town they're vacationing in is being plagued in an unusual fashion by parasitic aliens from outer space.
Votes: 85,556 | Gross: $33.72M
31. Doomsday (2008)
R | 105 min | Action, Sci-Fi, Thriller
A futuristic action thriller where a team of people work to prevent a disaster threatening the future of the human race.
Votes: 69,833 | Gross: $10.96M
32. The Devils (1971)
R | 111 min | Biography, Drama, History
In 17th-century France, Father Urbain Grandier seeks to protect the city of Loudun from the corrupt establishment of Cardinal Richelieu. Hysteria occurs within the city when he is accused of witchcraft by a sexually repressed nun.
33. Nosferatu the Vampyre (1979)
PG | 107 min | Drama, Horror
Count Dracula moves from Transylvania to Wismar, spreading the Black Plague across the land. Only a woman pure of heart can bring an end to his reign of horror.
34. Season of the Witch (2011)
PG-13 | 95 min | Action, Adventure, Fantasy
Fourteenth century knights transport a suspected witch to a monastery, where monks deduce her powers could be the source of the Black Plague.
Votes: 86,761 | Gross: $24.83M
35. Daybreakers (2009)
R | 98 min | Action, Fantasy, Horror
In the year 2019, a plague has transformed almost every human into vampires. Faced with a dwindling blood supply, the fractured dominant race plots their survival; meanwhile, a researcher works with a covert band of vamps on a way to save humankind.
Votes: 117,881 | Gross: $30.10M
37. Resident Evil: Retribution (2012)
R | 95 min | Action, Horror, Sci-Fi
Alice fights alongside a resistance movement to regain her freedom from an Umbrella Corporation testing facility.
Votes: 126,752 | Gross: $42.35M
38. Outbreak (1995)
R | 127 min | Action, Drama, Thriller
Army doctors struggle to find a cure for a deadly virus spreading throughout a California town that was brought to America by an African monkey.
Votes: 102,171 | Gross: $67.82M
39. The Omega Man (1971)
PG | 98 min | Action, Drama, Sci-Fi
Lone survivor, doctor Robert Neville, struggles to create a cure for the plague that wiped out most of the human race while fighting The Family, a savage luddite death cult formed by the zombie-like infected to erase the past.
Votes: 27,047 | Gross: $8.72M
44. The Last Man on Earth (1964)
Not Rated | 86 min | Drama, Horror, Sci-Fi
When a disease turns all of humanity into the living dead, the last man on earth becomes a reluctant vampire hunter.
45. Johnny Mnemonic (1995)
R | 96 min | Action, Drama, Sci-Fi
A data courier, literally carrying a data package inside his head, must deliver it before he dies from the burden or is killed by the Yakuza.
Votes: 63,336 | Gross: $19.08M
46. Exorcist: The Beginning (2004)
R | 114 min | Horror, Mystery, Thriller
Years before Father Lankester Merrin helped save Regan MacNeil's soul, he first encounters the demon Pazuzu in East Africa. This is the tale of Father Merrin's initial battle with Pazuzu and the rediscovery of his faith.
Votes: 32,019 | Gross: $41.82M
48. The Masque of the Red Death (1964)
Not Rated | 89 min | Horror
A European prince terrorizes the local peasantry while using his castle as a refuge against the "Red Death" plague that stalks the land.
49. The Andromeda Strain (1971)
G | 131 min | Sci-Fi, Thriller
A team of top scientists work feverishly in a secret, state-of-the-art laboratory to discover what has killed the citizens of a small town and learn how this deadly contagion can be stopped.
50. Anonymous (I) (2011)
PG-13 | 130 min | Drama, Thriller
The theory that it was in fact Edward De Vere, Earl of Oxford, who penned Shakespeare's plays. Set against the backdrop of the succession of Queen Elizabeth I and the Essex rebellion against her.
Votes: 38,208 | Gross: $4.46M