Nick is about to tell Nicky Jr. the "story of Dangerous Dan McGoup" as a good-night tale--an allusion to the character "Dangerous Dan McGrew" from Robert W. Service's famous poem "The Shooting of Dan McGrew". Nick, however, never gets to tell the story of the shooting--instead, inspired by Nicky's old-fashioned toy pistol, he rushes off chasing another clue.
Leon Ames was supposed to reprise his role as Edgar Draque from the previous installment of the series, The Thin Man Goes Home (1944). When Helen Vinson, who played his wife in the previous movie, was unavailable, the Draques were changed to the Talbins. This led to an unusual occurrence--an actor playing different characters within a film series, in back-to-back entries.
The last film for Myrna Loy at MGM, where she had made the majority of her films since the 1930s. In her autobiography she stated this picture was a "lackluster finish to a great series", and that she "hated" it.