Cheyenne witnesses a murder as he enters a town. He has come to pick up the son of a friend who is despised by his dad because he fought for the north. When the sheriff takes no interest in the murder, Cheyenne tries to help the widow.
Deputized by Pinkerton, Cheyenne escorts an old friend, now a convict, to his stolen $30K. Wes, shot and killed on the way, says the only clue is his now grown son who wants nothing to do with his pa he always believed was a coward.
Cheyenne is taking freight into Mexico during the rebellion but his real job is transporting an agent from the U.S. government. They are stopped by government troops but Cheyenne only is rescued by an old foe who works for the rebellion.
Cheyenne, a Deputy U.S. Marshal, is sent to a town to bring law and order after the sheriff there is killed. He finds one man runs the town and is stealing it blind. Due to jealousy he kills a man but Cheyenne needs proof to stop him.
Cheyenne befriends a wealthy rancher who makes Cheyenne the trustee of his estate until his son can be found if he dies. The man is killed in a mine incident with Cheyenne wounded. After healing, he finds another man has taken his place.
Cheyenne takes the foreman job at a ranch run by a hardheaded rancher with a crippled daughter and a stepson. The rancher ran off the last foreman due to his attentions toward his daughter. Cheyenne soon questions the rancher's actions.