The man playing Dr. Baines is Gordon McLendon. He was the uncredited executive producer and financier of this and its companion feature The Giant Gila Monster (1959). He owned radio stations and a chain of theaters in Texas.
A sequel, Return of the Killer Shrews, was produced in 2012, again starring Best as Thorne Sherman. Bruce Davison took the role of Jerry. The film also starred John Schneider and Rick Hurst, Best's co-stars in The Dukes of Hazzard. The length of time between the original film's release and the sequel's release (over 54 years) is one of the longest between film sequels in history.
Shot at Cielo Ranch, a 100-acre estate on the shore of Lake Lewisville (just North of Dallas, Texas) which was owned by star/producer Gordon McLendon (Dr. Baines). McLendon's family sold the ranch in the late 1990s and it was turned into an upscale housing development.
At one point Thorne says they should open the windows in the house because of the approaching hurricane. It was a popular belief at one time that opening windows during a hurricane or tornado would equalize the extreme air pressure and save houses from being destroyed. This has since been found to be a myth.