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Lorenzo's Oil (1992) Poster

(1992)

Trivia

Lorenzo Odone, who doctors had predicted would die in childhood, died on Friday, May 30, 2008, one day after his 30th birthday.
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Although a medical drama might seem an odd choice for the director of the "Mad Max" movies, George Miller is in fact a qualified doctor.
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Don Suddaby (himself) is the actual British biochemist that has synthesized the pure oil (erucic acid) that was used to treat Lorenzo. He was born in Kingston upon Hull, England, where he has a street named after him, "Suddaby Close", which runs adjacent to "Lorenzo Way".
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Michaela Odone died on June 10, 2000, of lung cancer. Eight years before her son finally succumbed to ALD (adrenoleukodystrophy).
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Based on a true story.
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Producer and Director George Miller also co-wrote the script. What with his medical background, it lends this movie a considerable accuracy when it comes to the progressive symptoms of ALD (adrenoleukodystrophy).
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Zack O'Malley Greenburg (Lorenzo) never acted again after this movie.
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Lorenzo was played by four actors and two actresses in this movie.
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In a 2014 interview at the Florida Film Festival, Susan Sarandon said that this movie was originally conceived and shot with the intent that as Lorenzo got sicker and sicker, the movie would fade from color to black-and-white. However, the production ran out of the money needed to process the film in that way, and the movie ended up being in color from beginning to end. She also said that this was actually the second movie in her career for which this had happened, that originally, The Rocky Horror Picture Show (1975) was supposed to be in black-and-white until the first appearance of Dr. Frank-N-Furter, when his red lips would have been the first item in color in the movie, but again, the production didn't have the money to process the film in that way, so the whole thing stayed in color.
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Michelle Pfeiffer was originally cast as Michaela Odone, but dropped out in order to play Catwoman in Batman Returns (1992), a role in which Susan Sarandon also expressed interest. The script for this movie was given to Sarandon, but she steadfastly refused to read it until she knew that Pfeiffer was no longer participating in this movie.
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Lorenzo's real-life secretary (Rita Chapman) had an uncredited walk on part in this movie.
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Theatrical movie debut of Laura Linney (Young Teacher).
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This is the only movie directed by George Miller that is not part of a larger franchise.
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George Miller's first movie since The Witches of Eastwick (1987). It reunited him with Susan Sarandon.
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Currently, the only movie of George Miller's that doesn't touch upon anything fantastical.
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The cast includes two Oscar winners: Susan Sarandon and Sir Peter Ustinov; and two Oscar nominees: Nick Nolte and Laura Linney.
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Nick Nolte says "Bravo" to Susan Sarandon. Jack Nicholson said the same thing to her in George Miller's The Witches of Eastwick (1987).
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