Frank Detorre is a slovenly zoo keeper, and simple father to the only young and bright girl named Shane, who catches a cold right after he swallowed a germ-ridden egg! The inside of his body is known as the "City of Frank". An unlikely hero of a policeman white blood cell, by the name of Osmosis Jones, works as a member of Immunity cell. But with that germ-ridden egg comes a mortal danger: Osmosis discovers Frank has really contracted a villainous and black-hearted deadly virus known as Thrax who arrives and is plotting to ultimately overheat Frank's body, killing him from the inside out! Thrax is motivated by trying to become the nastiest new virus, attempting to kill each new victim faster than the previous. His grandiose plan for Frank is death in 48 hours, breaking previous medical records! Meanwhile the pill that Frank took, Drix arrives in the body and covers Frank's throat with ice to cover the irritation. Osmosis Jones becomes his newest partner. Now it's all up to only ...Written by
Anthony Pereyra <email@example.com>
Sherri Howard, Holly Robinson, Camryn Manheim and Paula Abdul were considered for the role of Leah. See more »
When Frank is talking to his daughter by the monkey cage, his lunch box is lying on its side. In the next shot, the bag is standing up. See more »
[the cold pill arrives in the stomach]
Wow, this is huge.
Don't be all impressed, 'cause 99% of that is just sugar you know.
Yeah, and 99% of you is just stupid.
Ooh, like I haven't heard that one before.
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The opening credits are shown on strands on amoeba. See more »
The DVD release contains three extended (and half-animated) scenes, all of which appear in cut-down form in the final edit:
Drix and Jones visit the eyes, while Drix complains that he has to visit the nose and the throat. Jones gets donuts and calls the infodesk on his cell phone while at the eyes.
Frank picks his nose during the dam-bursting sequence, and Jones saves Drix from ending up on Frank's fingertip. In the end, they're snorted back up into the sinuses.
The race to catch Thrax on his way to the uvula is extended; we see Thrax leap from his car and glide away. Then, after Jones takes the wrong turn, he takes a "shortcut" to the uvula by way of the esophogus, riding a massive acidic Frank-belch up the throat.
When you mention the title of this film to someone, they just look at you and say "What?".
Yeah, nobody went to see this film when it came out. I think it's because how do you market a film like this? Since this takes place in the human body, there's all kinds of gross out humour in it. Some of it is too much for a PG rated film.
That's my biggest problem with this film and why it wasn't marketed very well. It's gross. The scene where the nose dam breaks and a giant tidal wave of snot comes out is not what you're mean to see in a family film. Especially on the big screen. The scene where Frank vomits on the teacher and it is shown in a newspaper headline, we actually see the vomit. You don't show people vomiting in a PG film. Not only that, but it's part of the story. Making gross out gags part of the story is not a good idea.
Also, the scene where the zit is ready to pop, we get a big giant close up on it which is enough to make anyone cringe.
It's almost like Panty and Stocking with Garterbelt. A show loaded with gross out humour. But that was for adults. This is meant to be a family film.
Now, the stuff I do like about it; the animation is great, it's very creative, (making the stomach the airport, the brain is city hall, the armpits are the steam room, I could go on)Laurence Fishburne was fantastic as Thrax. I kept forgetting it was him. Even if you don't like this film, you have to admit, Thrax is awesome. The music's great too. I like all the body puns as well.
Not a film for everyone, but has gained a cult following on DVD.
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