In her opening monologue, host Chelsea Handler talks about how to sustain a long term relationship. Chelsea and her round table panelists Chris Franjola, JC Coccoli and Jo Koy discuss Lil' Wayne's feud with the Miami Heat basketball team, Honey Boo Boo's gay uncle using her celebrity and photos of his penis to hook up on Grindr, a hypnotist who says he can make a straight man gay, Hooters in Tokyo and Hello Kitty's joint promotion, and Chris' altercation at a New York City bar. In their next Oscar nominated Best Picture movie review, the Keshishians talk about Lincoln (2012) and Silver Linings Playbook (2012). And Chelsea chats with guests Starsky & Cox (Stella Starsky and Quinn Cox) about their books "Sextrology" and "Cosmic Coupling". They also provide their predictions on Chelsea's future as she turns thirty-eight on Monday, those predictions on her love life and that of those around her such as Chuy and Roy.