While fighting with their own personal complications, Syd and McKenna try to find the killer of a transgender woman; Syd must face her past as the hunt for Knox intensifies; McKenna helps Izzy deal with her grief.
Nancy's past keeps getting more interesting. The Bens continue to investigate Squeakie's murder and the heist. Bishop gets targeted to try and get to Knox. Carlene becomes more interesting and powerful.
Carlene makes a power play and deals with the consequences. The DEA makes things difficult for the team. Warren tries to break from Carlene. Syd, Nancy and the Bens search for Carlene. Isabel gets to face her Demon.