Some establishing shots and scenes with a few characters are filmed on weekends at Bellevue Hospital Center, the New York City hospital about which Dr. Eric Manheimer wrote his memoir, "Twelve Patients: Life and Death at Bellevue Hospital." Bellevue hospital reopened in 2013 after months of renovations following flood damage caused by Hurricane Sandy in 2012. The facility's iconic modern atrium encloses its original stone facade, including the archway emblazoned with the word "Administration" that's seen in the show.
New Amsterdam is based to some extent on Dr. Eric Manheimer's memoir "Twelve Patients: Life and Death at Bellevue Hospital." Dr. Manheimer has been the Medical Director of Bellevue Hospital for over 13 years and is a Clinical Professor at the New York University School of Medicine.
Dr. Max Goodwin states that New Amsterdam is "the oldest public hospital in America." Bellevue Hospital Center, on which New Amsterdam is based, is in fact the oldest public hospital in the country, dating back to 1736.
The hospital on which the show is based was founded in 1736. In 1811 the city purchased about six acres of the Kip's Bay Farm along the East River. Belle Vue Place, along one border, already contained a building - the first to bear the name of Belle Vue Hospital. Later the spelling was changed to Belleview.
Freema Agyeman (Helen Sharpe) had played another medical doctor Martha Jones in Doctor Who. In a Doctor Who novel featuring Martha, The Last Dodo published in 2007, its author Jacqueline Rayner wrote that Martha found medical dramas hilarious after she started as a medical student at a hospital. New Amsterdam is one such medical drama although the publication of the Doctor Who novel came more than a decade before the debut of New Amsterdam with Freema Agyeman in 2018.